Cardiology

Hypertension

Changed

Cutoff is now ≥130/80 on every method. Stop 135/85 automated office blood pressure. Diabetes Canada still prints <130/80; that is a Canada conflict, not the Québec rule.

Diagnose

  • INESSS Institut national d'excellence en santé et services sociaux
  • HC Hypertension Canada
  • DC Diabetes Canada
DecisionGuideline
Diagnose
≥130/80 Validated automated device.
  • Office equals home equals daytime ambulatory monitoring.

INESSS 2026 opens in a new tabCMAJ opens in a new tabHypertension Canada diagnosis opens in a new tab

How to measure
5 minutes seated rest 3 readings at 1-minute intervals. Average all.

CMAJ opens in a new tabINESSS 2026

Confirm
Do not diagnose on a single reading Confirm with home blood pressure or ambulatory monitoring. If out-of-office is not feasible, repeat standardized office blood pressure at another visit.

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Start drugs
≥140/90 any risk: start drugs
  • Systolic 130–139: drugs only if high cardiovascular risk.
  • Else lifestyle;
  • reassess 3–6 months.

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<130
Systolic
Systolic <130Systolic target is under 130 mm Hg if tolerated. No diastolic target once systolic is at goal. Isolated diastolic above 80 with systolic already under 130 is uncommon and does not clearly raise event risk; lifestyle first, and drug intensification only after shared decision because the evidence is lacking.
  • No diastolic target once systolic is at goal.
  • Titrate every 3–4 weeks.

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Diabetes
DiffersBlood pressure
Systolic <130, no diastolic Diabetes is high cardiovascular risk, so drugs from 130–139.

INESSS 2026

<130/80 Still posted.
  • Do not prefer this in Québec.

Chapter 26 opens in a new tabDiabetes Canada 2018

135/85
DiffersOld automated office
Do not use 135/85

INESSS 2026

Automated office ≥135/85 Historical only.

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High cardiovascular risk

Drugs from systolic 130–139
  • INESSS Institut national d'excellence en santé et services sociaux
  • HC Hypertension Canada
DecisionGuideline
Age
≥75

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Cardiovascular disease
Differs
Coronary disease, heart failure, stroke, peripheral artery disease, atrial fibrillation, aneurysm

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Coronary disease, heart failure, stroke, peripheral artery disease Box 1 does not list atrial fibrillation or aneurysm.

Hypertension Canada 2025

Diabetes
Type 1 or type 2

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Kidney disease
eGFR <60 or uACR ≥3 mg/mmol

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Score
Framingham ≥20%

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Investigate

After the diagnosis is confirmed

Baseline tests for risk and end-organ damage. Repeat lipids and glucose on the usual screening interval, not at every visit.

  • INESSS Institut national d'excellence en santé et services sociaux
  • HC Hypertension Canada
DecisionGuideline
Blood
Sodium, potassium, creatinine, eGFR
  • Fasting glucose or HbA1c.
  • Lipids.

Already drawn

  • Use results from the last 3 months if already done.

CMAJ opens in a new tabINESSS 2026

Urine
Dipstick or urinalysis, plus uACR

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Electrocardiogram
12-lead electrocardiogram

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Treat

Lifestyle first. Then combination drugs. INESSS 2026 reminder names classes only. Hypertension Canada 2025 publishes a suggested start below. Titration and renal adjustment stay in the official protocol.

  • INESSS Institut national d'excellence en santé et services sociaux
  • HC Hypertension Canada
DecisionGuideline
Lifestyle
First-line for everyone Food, sodium, activity, alcohol, nicotine, sleep, stress.
  • Keep this even after drugs start.

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First drugs
Differs
ACE inhibitor or angiotensin receptor blocker plus a thiazide
  • Prefer one pill.
  • Monotherapy only if hypotension is likely.
  • Do not combine an ACE inhibitor with an angiotensin receptor blocker.

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Two of three classes
  • ACE inhibitor or angiotensin receptor blocker, thiazide, or dihydropyridine calcium channel blocker.
  • ACE inhibitor or angiotensin receptor blocker plus a calcium channel blocker is also first-line here.

CMAJ opens in a new tabHypertension Canada 2025

Still high
Add a dihydropyridine calcium channel blocker
  • Titrate or add every 3–4 weeks.
  • Aim for target in 3–6 months.

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Resistant
Spironolactone and/or refer Check renin and aldosterone before spironolactone.

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Do not
No beta-blocker first-line Uncomplicated hypertension.
  • Keep a beta-blocker if angina or heart failure.

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Hypertension Canada 2025 suggested start
DrugDoseDuration
Irbesartan / hydrochlorothiazide150/12.5 mg PO DIE (half of 300/25 mg)Ongoing

Follow-up

  • INESSS Institut national d'excellence en santé et services sociaux
  • HC Hypertension Canada
DecisionGuideline
Follow-up
Every 3–4 weeks while titrating
  • Aim for the target in 3–6 months.
  • Creatinine rise >30% after a drug change needs review.

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Reviewed 24 August 2026 against the official sources below.

Sources