Family medicine

Anxiety

The INESSS outil of 2 Oct 2026 is a usage-optimal tool for a first benzodiazepine prescription, not a GUO or a PMN. It does not apply to someone already taking a benzodiazepine.

Treat

Open the outil PDF for molecule choice and the milligram tables (annex III). The full list of situations where starting a benzodiazepine is discouraged is on Insomnia.

  • INESSS Institut national d'excellence en santé et services sociaux
DecisionGuideline
Scope
Who
Adults not currently taking a benzodiazepine, when considering a first benzodiazepine prescription for insomnia or an anxiety disorder.

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Exclusions
Does not apply to:pregnancy or breastfeeding; already on a benzodiazepine; critical care; palliative or end-of-life care; alcohol withdrawal; peri-procedural very short use; an acute psychiatric episode that needs a hospital stay.

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First-line
Anxiety
First-line for an anxiety disorder: interventions based on cognitive-behavioural approaches and/or antidepressants (SSRI or SNRI).

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Severe symptoms
A rapid-acting anxiolytic may be considered short-term, as an add-on, when symptoms are severe.

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First weeks
In an anxiety disorder, a benzodiazepine may be considered in the first weeks of care, to cover antidepressant or psychosocial onset delay and possible early anxiety worsening on an antidepressant.

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Rapid-acting
Benzodiazepines are the only rapid-acting anxiolytics usable in severe anxiety disorders (per the outil).

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If a benzodiazepine is chosen
Stewardship
Shared decision. Choose the molecule and the dose appropriately. Prescribe the shortest possible duration (max. 4 weeks). Prefer PRN only. Plan the end of treatment from the first prescription. Avoid systematic renewals.

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Continue
Continue first-line treatments even if a benzodiazepine is started.

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Doses
Molecule selection, starting milligrams, and the annex III sedative-hypnotic table: open the outil PDF. Check the live RAMQ Liste for coverage.

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Already taking one
Deprescribing
This outil covers a first prescription only. It does not replace deprescribing for someone already taking a benzodiazepine. CCSMH 2019 (older adults; BZRA duration, taper, and deprescribing) and CCSMH 2024 (late-life anxiety) remain in force for those scopes.

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Follow-up

  • INESSS Institut national d'excellence en santé et services sociaux
DecisionGuideline
Follow-up
Follow up within 2 to 4 weeks after the first benzodiazepine prescription.

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Reviewed 5 October 2026 against the official sources below.

Sources